AUP1
ancient ubiquitous protein 1
Human AUP1 (550), Mouse Aup1 (11993), Rat Aup1 (680423), chicken AUP1 (769206), Zebrafish aup1 (324654), sheep AUP1 (101119707), cow AUP1 (509130), domestic cat AUP1 (101087730), naked mole-rat Aup1 (101724866), domestic guinea pig Aup1 (100734345)
- Human(550) Summary: This gene encodes a protein that contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. The protein encoded by this gene has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits. These subunits play a crucial role in the integrin alpha(IIb)beta(3) inside-out signalling in platelets and megakaryocytes that leads to platelet aggregation and thrombus formation. This gene overlaps the gene for mitochondrial serine protease 25. [provided by RefSeq, Jul 2008]
- Mouse(11993) ancient ubiquitous protein 1
- Rat(680423) ancient ubiquitous protein 1
- chicken(769206) ancient ubiquitous protein 1
- Zebrafish(324654) ancient ubiquitous protein 1
- sheep(101119707) ancient ubiquitous protein 1
- cow(509130) ancient ubiquitous protein 1
- domestic cat(101087730) ancient ubiquitous protein 1
- naked mole-rat(101724866) ancient ubiquitous protein 1
- domestic guinea pig(100734345) ancient ubiquitous protein 1
- dog(475783) ancient ubiquitous protein 1
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