ACR
acrosin
Synonyms:
Species:
Human ACR (49), Mouse Acr (11434), Rat Acr (24163), chicken ACR (426864), dog ACR (606765), domestic cat ACR (101083949), cow ACR (280711), Domestic Rabbit ACR (100009184), domestic guinea pig Acr (100717414)
UniProtKB ID:
Gene ID:
- Human(49) Summary: Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids. [provided by RefSeq, Jul 2008]
- Mouse(11434) acrosin prepropeptide
- Rat(24163) acrosin
- chicken(426864) acrosin
- dog(606765) acrosin
- domestic cat(101083949) acrosin
- cow(280711) acrosin
- Domestic Rabbit(100009184) acrosin
- domestic guinea pig(100717414) acrosin
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