ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
Synonyms:
ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP
Species:
Human ABCB11 (8647), Mouse Abcb11 (27413), Rat Abcb11 (83569), Horse ABCB11 (100052359), domestic cat ABCB11 (101085737), dog ABCB11 (488390), chicken ABCB11 (424170), naked mole-rat Abcb11 (101716542), domestic guinea pig Abcb11 (100337637), Domestic Rabbit ABCB11 (100008767) ...More
UniProtKB ID:
Gene ID:
- Human(8647) Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq, Jul 2008]
- Mouse(27413) ATP-binding cassette, sub-family B (MDR/TAP), member 11
- Rat(83569) ATP-binding cassette, subfamily B (MDR/TAP), member 11
- Horse(100052359) ATP-binding cassette, sub-family B (MDR/TAP), member 11
- domestic cat(101085737) ATP-binding cassette, sub-family B (MDR/TAP), member 11
- dog(488390) ATP-binding cassette, sub-family B (MDR/TAP), member 11
- chicken(424170) ATP-binding cassette, sub-family B (MDR/TAP), member 11
- naked mole-rat(101716542) ATP-binding cassette, sub-family B (MDR/TAP), member 11
- domestic guinea pig(100337637) ATP-binding cassette, sub-family B (MDR/TAP), member 11
- Domestic Rabbit(100008767) ATP-binding cassette, sub-family B (MDR/TAP), member 11
- sheep(101121238) ATP-binding cassette, sub-family B (MDR/TAP), member 11
- cow(531150) ATP-binding cassette, sub-family B (MDR/TAP), member 11
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ABCB11 Antibody, clone 10D4.1, clone 10D4.1, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
esiRNA
Product Number
Description
Species