- [Lessons from the novel renoprotective studies with antihypertensive drugs].
[Lessons from the novel renoprotective studies with antihypertensive drugs].
Orvosi hetilap (2013-02-12)
László Bajnok
PMID23395787
ABSTRACT
From the evaluated ONTARGET, ALTITUDE, ACCOMPLISH, ROADMAP, and ACCORD-BP studies a conclusion can be drawn that though microalbuminuria/proteinuria is a strong epidemiological biomarker, in interventional studies it is not necessarily a reliable surrogate endpoint as actual renal function may change in an opposite way. Namely, some therapeutic measures improving microalbuminuria/proteinuria may actually worsen renal function. In case of procedures such as blood pressure lowering or measure of RAS blockade an optimum point on a J-curve may exist.
MATERIALS
Product Number
Brand
Product Description
SKU
Pack Size
Availability
Price
Quantity
SKU
Pack Size
Availability
Price
Quantity
Amlodipine for peak identification, European Pharmacopoeia (EP) Reference Standard
SKU
Pack Size
Availability
Price
Quantity
Amlodipine besylate, European Pharmacopoeia (EP) Reference Standard
SKU
Pack Size
Availability
Price
Quantity