A6779

Adenosine 5′-triphosphate, periodate oxidized sodium salt

≥97%

• Synonym(s): oATP, Adenosine 5′-triphosphate-2′,3′-dialdehyde
• Empirical Formula (Hill Notation): C₁₀H₁₄N₅O₁₃P₃
• CAS Number: 71997-40-5
• Molecular Weight: 505.17
• MDL number: MFCD00056956
• UNSPSC Code: 41106305
• eCl@ss: 32160414
• PubChem Substance ID: 24891137
• NACRES: NA.51

Properties

• biological source: bacterial (corynebacterium sp)
• Assay: ≥97%
• form: powder
• storage temp.: −20°C
• SMILES string: [Na].Nc1ncnc2n(cnc12)[C@H](O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C=O)C=O
• InChI: 1S/C10H14N5O13P3.Na.H/c11-9-8-10(13-4-12-9)15(5-14-8)7(2-17)26-6(1-16)3-25-30(21,22)28-31(23,24)27-29(18,19)20;;/h1-2,4-7H,3H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;/t6-,7+;;/m0../s1
• InChI key: IHQATUPGVKMGLT-AUCRBCQYSA-N

Description

General description

Adenosine 5′-triphosphate 2′,3′ dialdehyde is a derivative of dialdehyde.

Application

Adenosine 5′-triphosphate, periodate oxidized sodium salt has been used:

• as an antagonist of the purinergic receptor, P2 × 7 to inhibit P2 × 7 pathway
• as a nonspecific agonist to assess the activity of P2×₇-R by the mobilization of Ca²⁺
• to evaluate the physiological significance of elevated intracellular ATP levels
• increased P2rx7 expression for osteoclastogenesis in Flcn-deficient cells

Biochem/physiol Actions

Adenosine 5′-triphosphate 2′,3′ dialdehyde is considered as an inhibitor of P2 × 7 receptor.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves