PHL80324

Quassin

phyproof^® Reference Substance

• Synonym(s): Nigakilaktone D
• Empirical Formula (Hill Notation): C₂₂H₂₈O₆
• CAS Number: 76-78-8
• Molecular Weight: 388.45
• MDL number: MFCD00273126
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: primary reference standard
• product line: phyproof^® Reference Substance
• Assay: ≥95.0% (HPLC)
• manufacturer/tradename: PhytoLab
• application(s): food and beverages
• format: neat
• InChI: 1S/C22H28O6/c1-10-7-14(26-5)20(25)22(4)12(10)8-15-21(3)13(9-16(23)28-15)11(2)18(27-6)17(24)19(21)22/h7,10,12-13,15,19H,8-9H2,1-6H3/t10-,12+,13+,15-,19+,21-,22+/m1/s1
• InChI key: IOSXSVZRTUWBHC-LBTVDEKVSA-N

Description

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Application

• Quassin Extract for Cancer Research: Quassin extract, recognized for its potent anticancer properties, is utilized in scientific research to study its efficacy in inhibiting the growth of various cancer cell lines. Its bioactive compounds are critical in exploring new therapeutic avenues for cancer treatment, particularly in breast, lung, and prostate cancers (Reference 1).


• Pharmacological Applications in Malaria: Quassin has shown promising results as a potential anti-malarial agent. Research focuses on its ability to disrupt the life cycle of malaria parasites, offering a basis for developing novel antimalarial drugs that could help combat resistance to current therapies (Reference 2).


• Biochemical Research on Metabolic Disorders: In the realm of metabolic disorder research, quassin is studied for its effects on glucose and lipid metabolism. This research is pivotal for understanding how quassin can modulate metabolic pathways and potentially offer benefits for treating diseases like diabetes and obesity (Reference 3).


• Development of Bioanalytical Methods: Quassin is utilized in the development of new bioanalytical methods for natural products. High-purity quassin standards are essential for validating the sensitivity and specificity of analytical techniques used in the quantification and characterization of plant-derived compounds (Reference 4).


• Therapeutic Research in Biochemistry: Quassin′s role extends to biochemical research where it is used to explore its therapeutic potentials, including its anti-inflammatory and antioxidative activities. This research helps in identifying and developing quassin-based formulations for various inflammatory and oxidative stress-related conditions (Reference 5).

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Precautionary Statements: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable