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  • Calcium and vitamin D in the prevention and treatment of osteoporosis - a clinical update.

Calcium and vitamin D in the prevention and treatment of osteoporosis - a clinical update.

Journal of internal medicine (2006-05-18)
S Boonen, D Vanderschueren, P Haentjens, P Lips
ABSTRACT

Combined calcium and vitamin D supplementation is an essential component of the management of osteoporosis, supported by a strong scientific rationale. The types of individuals who should receive calcium and vitamin D supplements are those: (i) patients with documented osteoporosis receiving antiresorptive or anabolic treatment; (ii) patients receiving glucocorticoids; and (iii) individuals with or at high risk of calcium and/or vitamin D insufficiencies, in particular older women and men. This article describes the evidence base that supports targeting these groups. Benefits are most apparent when 800 IU day(-1) vitamin D is complemented with a dose of 1000-1200 mg day(-1) elemental calcium. Compliance is also key to optimizing clinical efficacy.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Calcium, SAJ first grade, ≥99.5%
Sigma-Aldrich
Calcium, dendritic pieces, purified by distillation, 99.99% trace metals basis
Sigma-Aldrich
Calcium, granular, 99%
Sigma-Aldrich
Calcium, pieces, <1 cm, 99%
Sigma-Aldrich
Calcium, turnings, 99% trace metals basis
Sigma-Aldrich
Calcium, dendritic pieces, purified by distillation, 99.9% trace metals basis