Skip to Content
Merck
All Photos(1)

Key Documents

1576708

USP

Propylene glycol

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

1,2-Propanediol, Propylene glycol

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
CH3CH(OH)CH2OH
CAS Number:
Molecular Weight:
76.09
Beilstein:
1340498
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

vapor density

2.62 (vs air)

vapor pressure

0.08 mmHg ( 20 °C)

API family

propylene glycol

autoignition temp.

779 °F

expl. lim.

12.5 %

manufacturer/tradename

USP

refractive index

n20/D 1.432 (lit.)

bp

187 °C (lit.)

mp

−60 °C (lit.)

density

1.036 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CC(O)CO

InChI

1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3

InChI key

DNIAPMSPPWPWGF-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Propylene glycol USP reference standard intended for use in specified quality tests and assays.

Also used to prepare standard stock, standard, sample, system suitability, and sensitivity solution for assay and impurity analysis according to the given below monographs of United States Pharmacopeia (USP):
  • Propylene Glycol Dilaurate
  • Phenytoin Sodium Injection
  • Hydroxypropyl Betadex
  • Butylene Glycol

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

219.2 °F - closed cup

Flash Point(C)

104 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Butylene Glycol
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(5), 5653-5653 (2020)
Hydroxypropyl Betadex
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 32(5), 5818-5818 (2020)
Phenytoin Sodium Injection
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 46(5), 3534-3534 (2020)
Propylene Glycol Dilaurate
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 35(3), 5989-5989 (2013)
J O Funk et al.
Contact dermatitis, 31(4), 236-241 (1994-10-01)
Evaluation of dermatitis associated with propylene glycol application or ingestion remains a challenge. The research dealing with skin reactions to propylene glycol is revisited and new aspects for future research are outlined. Based on literature review and our own observations

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service