840457C

16:0-18:1 PG

Avanti Research^™ - A Croda Brand

• Synonym(s): 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); POPG; PG(16:0/18:1(9Z)); 110650
• Empirical Formula (Hill Notation): C₄₀H₇₆O₁₀PNa
• CAS Number: 268550-95-4
• Molecular Weight: 770.99
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• description: 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), chloroform
• Assay: >99% (TLC)
• form: liquid
• packaging: pkg of 1 × 2.5 mL (840457C-25mg); pkg of 2 × 20 mL (840457C-1g); pkg of 2 × 4 mL (840457C-200mg); pkg of 5 × 4 mL (840457C-500mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• concentration: 10 mg/mL (840457C-25mg); 25 mg/mL (840457C-1g); 25 mg/mL (840457C-200mg); 25 mg/mL (840457C-500mg)
• lipid type: phospholipids
• shipped in: dry ice
• storage temp.: −20°C
• InChI: 1S/C40H77O10P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-40(44)50-38(36-49-51(45,46)48-34-37(42)33-41)35-47-39(43)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h17-18,37-38,41-42H,3-16,19-36H2,1-2H3,(H,45,46);/q;+1/p-1/b18-17-;/t37?,38-;/m1./s1
• InChI key: FJXDNGDRHUDFST-XQYKCTAGSA-M

Description

General description

Phosphoglyceride (PG) are also referred as glycerophospholipid. It is an important component of membrane bilayers. It has three-carbon backbone of glycerol, two long-chain fatty acids, esterified to hydroxyl groups on carbons 1 and 2 of the glycerol and phosphoric acid esterified to the C₃ hydroxyl group of glycerol. It is found at high levels in the membranes of all cells and at low levels in fat stores. 16:0-18:1 PG/1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (POPG) is an anionic lipid, which possesses one negative charge per lipid.

Application

16:0-18:1 PG has been used in liposome preparation. It is suitable for use as a component in monoolein to treat purified β2-adrenergic receptor (β2AR)-T4 lysozyme (T4L)- Gαs α5 helix (GsCT)-CC chimera protein and in lipid vesicle preparation.

Biochem/physiol Actions

Phosphoglycerides (PG)/glycerophospholipids play a key role in cell signaling systems. It also serves as an anchor for proteins in cell membranes.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (840457C-1g)

5 mL Clear Glass Sealed Ampule (840457C-200mg)

5 mL Clear Glass Sealed Ampule (840457C-25mg)

5 mL Clear Glass Sealed Ampule (840457C-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Precautionary Statements: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Target Organs: Central nervous system, Liver,Kidney
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable