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  • Silver sulfadiazine: an antibacterial agent for topical use in burns. A review of the literature.

Silver sulfadiazine: an antibacterial agent for topical use in burns. A review of the literature.

Scandinavian journal of plastic and reconstructive surgery (1984-01-01)
S Hoffmann
ABSTRACT

Topical antibacterial treatment is of major importance in the burn patient. Silver sulfadiazine is an effective agent with low toxicity and few side effects. Deposition of silver in tissues, and absorption of sulfadiazine are both minimal. Present and future problems are represented by the emergence of resistant Gram negative bacilli, including Pseudomonas aeruginosa. The development of related metal sulfadiazines to be used against resistant bacteria is on an investigational stage, and clinical trials are few. Silver sulfadiazine may be used in a variety of other conditions than burns.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Silver(I) sulfadiazine, 98%
Supelco
Sulfadiazine, VETRANAL®, analytical standard
Sigma-Aldrich
Sulfadiazine, 99.0-101.0%
USP
Silver sulfadiazine, United States Pharmacopeia (USP) Reference Standard
Supelco
Sulfadiazine, Pharmaceutical Secondary Standard; Certified Reference Material
USP
Sulfadiazine, United States Pharmacopeia (USP) Reference Standard
Sulfadiazine for identification of impurity F, European Pharmacopoeia (EP) Reference Standard
Sulfadiazine, European Pharmacopoeia (EP) Reference Standard