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Key Documents

PLA0167

Sigma-Aldrich

Rabbit anti-TRRAP Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

350/400 kDa PCAF-associated factor, PAF350/400, PAF400, STAF40, TR-AP, Tra1, tra1 homolog

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

grade

Powered by Bethyl Laboratories, Inc.

species reactivity

mouse, human

technique(s)

immunoprecipitation (IP): 2-5 μg/mg
western blot: 1:2,000- 1:10,000

accession no.

AAD04629.1

UniProt accession no.

Q9Y4A5

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

rabbit ... TRRAP(8295)

Immunogen

The epitope recognized by PLA0167 maps to a region between residue 3809 and 3859 of human transformation/transcription domain-associated protein using the numbering given in entry AAD04629.1 (GeneID 8295).

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Other Notes

TRRAP is a common component of histone acetyltransferase (HAT) complexes and functions as an adaptor protein that recruits HAT complexes to chromatin during transcription, replication, and DNA repair. TRRAP has been shown to play a key role in c-Myc-mediated transcription and transformation. TRAPP has also been observed to interact with many other transcription factors including p53, E2F1, E2F4, and the E1A viral oncoprotein.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Bei Bu et al.
The EMBO journal, 39(1), e101259-e101259 (2019-09-21)
Psychiatric diseases are often accompanied by circadian disruptions, but the molecular underpinnings remain largely unclear. To address this, we screened genes that have been previously reported to be associated with psychiatric diseases and found that TRRAP, a gene associated with

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