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A6508

Sigma-Aldrich

L-Aspartic acid β-hydroxamate

>98%

Synonym(s):

AAH, HDX, LAH

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About This Item

Empirical Formula (Hill Notation):
C4H8N2O4
CAS Number:
Molecular Weight:
148.12
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

product name

L-Aspartic acid β-hydroxamate, serine racemase inhibitor

Quality Level

Assay

>98%

form

powder

color

white to yellow

application(s)

detection

storage temp.

−20°C

SMILES string

N[C@@H](CC(=O)NO)C(O)=O

InChI

1S/C4H8N2O4/c5-2(4(8)9)1-3(7)6-10/h2,10H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1

InChI key

ZBYVTTSIVDYQSO-REOHCLBHSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Véronique Sauvé et al.
Nature structural & molecular biology, 25(7), 623-630 (2018-07-04)
Mutations in the ubiquitin ligase parkin are responsible for a familial form of Parkinson's disease. Parkin and the PINK1 kinase regulate a quality-control system for mitochondria. PINK1 phosphorylates ubiquitin on the outer membrane of damaged mitochondria, thus leading to recruitment
Rane A Harrison et al.
Current opinion in structural biology, 41, 187-193 (2016-08-24)
Hydrogen-deuterium exchange (HDX) mass spectrometry (MS) can provide information about proteins that can be challenging to obtain by other means. Structure/function relationships, binding interactions, and the effects of modification have all been measured with HDX MS for a diverse and
N Thomasset et al.
International journal of cancer, 49(3), 421-424 (1991-09-30)
D and L isomers of aspartic acid beta-hydroxamate (respectively DAH and LAH) were compared for their in vitro and in vivo activity against the murine leukemia L5178Y and their tolerance in vivo in DBA/2 mice. DAH and LAH displayed comparable
Jie Zheng et al.
Nature communications, 8(1), 923-923 (2017-10-17)
The vitamin D receptor/retinoid X receptor-α heterodimer (VDRRXRα) regulates bone mineralization via transcriptional control of osteocalcin (BGLAP) gene and is the receptor for 1α,25-dihydroxyvitamin D
Yujiao Zhou et al.
Journal of immunology research, 2018, 9832467-9832467 (2018-08-18)
Dendritic cells (DCs) harboring tumor-associated antigen are supposed to be a potential immunotherapy for hepatocellular carcinoma (HCC). Aspartate-β-hydroxylase (AAH), an overexpressed tumor-associated cell surface protein, is considered as a promising biomarker and therapeutic target for HCC. In this study, we

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