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Key Documents

P9762

Sigma-Aldrich

3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine-4′,4′′-disulfonic acid sodium salt

Powder

Synonym(s):

5,6-Diphenyl-3-(2-pyridyl)-1,2,4-triazine-4′,4″-disulfonic acid sodium salt, PDT disulfonate

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About This Item

Empirical Formula (Hill Notation):
C20H13N4NaO6S2
CAS Number:
Molecular Weight:
492.46
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

product name

3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine-4′,4′′-disulfonic acid sodium salt, Indicator ligand

Quality Level

form

powder

color

yellow to yellow-green

mp

≥300 °C

solubility

H2O: 50 mg/mL

suitability

suitable for determination of iron

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].OS(=O)(=O)c1ccc(cc1)-c2nnc(nc2-c3ccc(cc3)S([O-])(=O)=O)-c4ccccn4

InChI

1S/C20H14N4O6S2.Na/c25-31(26,27)15-8-4-13(5-9-15)18-19(14-6-10-16(11-7-14)32(28,29)30)23-24-20(22-18)17-3-1-2-12-21-17;/h1-12H,(H,25,26,27)(H,28,29,30);/q;+1/p-1

InChI key

ZGVNYCXXBQPDPQ-UHFFFAOYSA-M

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General description

3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine-4′,4′′-disulfonic acid sodium salt is a chelating agent for ferrous iron. It is also known as Ferrozine.

Application

3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine-4′,4″-disulfonic acid sodium salt has been used in ferrozine chromogen solution, bioluminescence assay and in the measurement of Fe2+concentration in the reaction medium.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Optimisation of in vitro measurement of available iron from different fortificants in citric fruit juices.
Haro-Vicente JF, et al.
Food Chemistry, 98(4), 639-648 (2006)
Iron is involved in maintenance of circadian period length in Arabidopsis.
Chen YY, et al.
Plant Physiology (2013)
Behavior of phenolic antioxidants in a partitioned medium: Focus on linoleic acid peroxidation induced by iron/ascorbic acid system.
Bondet V, et al.
Journal of the American Oil Chemists' Society, 77(8), 813-813 (2000)
M W Reeves et al.
Journal of clinical microbiology, 14(1), 48-54 (1981-07-01)
A total of 13 egg lecithins, 12 beef heart lecithins, and 15 beef heart cardiolipins were assayed for the ability to function in the Venereal Disease Research Laboratory microflocculation test, as well as for purity, fatty acid composition, free amines
Bruno Alies et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 18(4), 1161-1167 (2011-12-23)
The association constant of ferrozine (5,6-diphenyl-3-(2-pyridyl)-1,2,4-triazine-4,4''-disulfonic acid) with Cu(I) to form the chromophoric [Cu(I)(Fz)(2)](3-) complex was determined by UV/Vis titration experiments in Hepes buffer (0.1 M, pH 7.4). An association constant close to 10(12) M(-2), which is significantly weaker than

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