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Iron(III) citrate tribasic monohydrate

18-20% Fe basis (T)

Synonym(s):

Ferric citrate monohydrate

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About This Item

Empirical Formula (Hill Notation):
C6H5FeO7 · H2O
CAS Number:
2338-05-8
Molecular Weight:
262.96
Beilstein:
4052503
EC Number:
219-045-4
MDL number:
MFCD00013098
UNSPSC Code:
12000000
PubChem Substance ID:
329756569
NACRES:
NA.21

Quality Level

100

form

solid

concentration

18-20% Fe (T)

anion traces

chloride (Cl-): ≤500 mg/kg

cation traces

Ca: ≤100 mg/kg
Cd: ≤50 mg/kg
Co: ≤50 mg/kg
Cu: ≤50 mg/kg
K: ≤500 mg/kg
Na: ≤200 mg/kg
Ni: ≤100 mg/kg
Pb: ≤50 mg/kg
Zn: ≤50 mg/kg

SMILES string

OC12CC(=O)O[Fe](OC(=O)C1)OC2=O

InChI

1S/C6H8O7.Fe/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);/q;+3/p-3

InChI key

NPFOYSMITVOQOS-UHFFFAOYSA-K

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Application

Iron(III) citrate tribasic monohydrate may be used as the source of iron, in one of the compositions, used during the preparation of perfusion solutions.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK7269
BCCH9404
BCCD4542
BCBZ5545
BCBT7358

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A E Gómez-Ayala et al.
Laboratory animals, 32(1), 72-79 (1998-03-03)
The effects of iron deficiency on the absorption of different dietary sources of iron were studied, together with the interactions between iron, calcium, phosphorus, magnesium, copper and zinc in the jejunum-ileum of control and iron-deficient rats. In this study, three
Tatsuya Fukushima et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(42), 16829-16834 (2012-10-03)
Citrate is a common biomolecule that chelates Fe(III). Many bacteria and plants use ferric citrate to fulfill their nutritional requirement for iron. Only the Escherichia coli ferric citrate outer-membrane transport protein FecA has been characterized; little is known about other
Petra Vukosav et al.
Analytica chimica acta, 745, 85-91 (2012-09-04)
A detailed study of iron (III)-citrate speciation in aqueous solution (θ=25°C, I(c)=0.7 mol L(-1)) was carried out by voltammetric and UV-vis spectrophotometric measurements and the obtained data were used for reconciled characterization of iron (III)-citrate complexes. Four different redox processes
Guus A M Kortman et al.
PloS one, 7(1), e29968-e29968 (2012-01-25)
Recent trials have questioned the safety of untargeted oral iron supplementation in developing regions. Excess of luminal iron could select for enteric pathogens at the expense of beneficial commensals in the human gut microflora, thereby increasing the incidence of infectious
Jamie P Dwyer et al.
American journal of kidney diseases : the official journal of the National Kidney Foundation, 61(5), 759-766 (2013-02-02)
Most dialysis patients require phosphate binders to control hyperphosphatemia. Ferric citrate has been tested in phase 2 trials as a phosphate binder. This trial was designed as a dose-response and efficacy trial. Prospective, phase 3, multicenter, open-label, randomized clinical trial.
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