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850457C

Avanti

16:0-18:1 PC

Avanti Research - A Croda Brand

Synonym(s):

1-hexadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phosphocholine; POPC; PC(16:0/18:1(9Z))

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About This Item

Empirical Formula (Hill Notation):
C42H82NO8P
CAS Number:
Molecular Weight:
760.08
UNSPSC Code:
51191904
NACRES:
NA.25

description

1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, chloroform

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850457C-25mg)
pkg of 2 × 20 mL (850457C-1g)
pkg of 2 × 4 mL (850457C-200mg)
pkg of 5 × 4 mL (850457C-500mg)

manufacturer/tradename

Avanti Research - A Croda Brand

concentration

10 mg/mL (850457C-25mg)
25 mg/mL (850457C-1g)
25 mg/mL (850457C-200mg)
25 mg/mL (850457C-500mg)

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O

InChI

1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1

InChI key

WTJKGGKOPKCXLL-VYOBOKEXSA-N

General description

POPC is typically considered one of the model lipids for biophysical experiments. The fatty acid composition, i.e., saturated chain in the sn-1 position and unsaturated chain in the sn-2 position, mimics mammalian phospholipid composition. Since the major constituent in Egg PC is 1-palmitoyl-2-oleoyl PC, POPC is an excellent synthetic substitute for EPC.

Application

16:0-18:1 PC has been used in liposome disruption assay to examine lytic properties of biomolecules. It has also been used to prepare liposomes.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850457C-1g)
5 mL Clear Glass Sealed Ampule (850457C-200mg)
5 mL Clear Glass Sealed Ampule (850457C-25mg)
5 mL Clear Glass Sealed Ampule (850457C-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Product No.
Description
Pricing

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Membrane lipid screen to identify molecular targets of biomolecules
Jimah JR, et al.
Bio-protocol, 7(15) (2017)
Liposome Disruption Assay to Examine Lytic Properties of Biomolecules.
Jimah JR, et al.
Bio-protocol, 7(15) (2017)
Tripta Bhatia et al.
ACS nano, 12(5), 4478-4485 (2018-04-17)
Giant unilamellar vesicles (GUVs) provide a direct connection between the nano- and the microregime. On the one hand, these vesicles represent biomimetic compartments with linear dimensions of many micrometers. On the other hand, the vesicle walls are provided by single
Ionization Properties of Phospholipids Determined by Zeta Potential Measurements
Sathappa M, et al.
Bio-protocol, 6(22) (2016)
Nicholas Skar-Gislinge et al.
Langmuir : the ACS journal of surfaces and colloids, 34(42), 12569-12582 (2018-09-22)
Phospholipid nanodiscs have quickly become a widely used platform for studies of membrane proteins. However, the molecular self-assembly process that ultimately should place a membrane protein inside a nanodisc is not well understood. This poses a challenge for a successful

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