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Synthesis of platinum(II) chiral tetraamine coordination complexes.

Journal of combinatorial chemistry (2006-09-12)
Adel Nefzi, Cornelia E Hoesl, Clemencia Pinilla, George B Kauffman, Gerald M Maggiora, Elena Pasquale, Richard A Houghten
ABSTRACT

The individual and combinatorial syntheses of individual as well as a mixture-based diversity of 195 112 platinum(II) coordination complexes of chiral tetraamines are described. The use of both solid-phase synthesis and solution phase follow-on approaches were found to best afford the title compounds.

MATERIALS
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Product Description

Sigma-Aldrich
Tetraammineplatinum(II) nitrate, 99.995% trace metals basis