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W224511

Sigma-Aldrich

Carvacrol

natural, 99%, FG

Synonym(s):

5-Isopropyl-2-methylphenol

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About This Item

Linear Formula:
(CH3)2CHC6H3(CH3)OH
CAS Number:
499-75-2
Molecular Weight:
150.22
FEMA Number:
2245
Beilstein:
1860514
EC Number:
207-889-6
Council of Europe no.:
2055
MDL number:
MFCD00002236
UNSPSC Code:
12164502
PubChem Substance ID:
329830467
Flavis number:
4.031
NACRES:
NA.21

grade

FG
Fragrance grade
Halal
Kosher
natural

Agency

follows IFRA guidelines
meets purity specifications of JECFA

reg. compliance

EU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
FDA 21 CFR 117

Assay

99%

refractive index

n20/D 1.522 (lit.)

bp

236-237 °C (lit.)

mp

3-4 °C (lit.)

density

0.976 g/mL at 20 °C (lit.)

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

no known allergens

fragrance allergen

carvacrol

Organoleptic

camphoraceous; woody; spicy

SMILES string

CC(C)c1ccc(C)c(O)c1

InChI

1S/C10H14O/c1-7(2)9-5-4-8(3)10(11)6-9/h4-7,11H,1-3H3

InChI key

RECUKUPTGUEGMW-UHFFFAOYSA-N

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General description

Carvacrol is one of the key constituents of basil and thyme essential oils. It is one of the compounds that may be responsible for antioxidant activities of these oils.

Application


  • Prophylactic efficacy of baicalin and carvacrol against Salmonella Typhimurium biofilm on food and food contact surfaces.: The study explores the effectiveness of carvacrol in preventing biofilm formation by Salmonella Typhimurium, with implications for food safety (Ashrafudoulla et al., 2024).


Signal Word

Danger

Hazard Statements

H302,H314,H411

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

>212.0 °F

Flash Point(C)

> 100 °C

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Rachel Spiering et al.
PloS one, 7(9), e46336-e46336 (2012-10-11)
Tolerogenic dendritic cells (DCs) can induce regulatory T cells and dampen pathogenic T cell responses. Therefore, they are possible therapeutic targets in autoimmune diseases. In this study we investigated whether mouse tolerogenic DCs are induced by the phytonutrient carvacrol, a
Laura Higueras et al.
Carbohydrate polymers, 97(2), 262-268 (2013-08-06)
The aim of this work was to design new polymer-based systems exhibiting an adjustable loading capacity of carvacrol depending on the film formulation. For this purpose, biocomposite films were developed employing chitosan (CS) as the polymer matrix and hydroxypropyl-β-cyclodextrins (HP-βCDs)
Josué de Moraes et al.
Parasitology research, 112(2), 603-610 (2012-10-23)
Blood flukes of the genus Schistosoma are the causative agents of human schistosomiasis, a debilitating disease that afflicts over 200 million people worldwide. Praziquantel is the drug of choice but concerns over praziquantel resistance have renewed interest in the search
Wei-Zhe Liang et al.
Toxicology, 303, 152-161 (2012-11-14)
Carvacrol is one of the main substances of essential oil which triggers intracellular Ca(2+) mobilization and causes cytotoxicity in diverse cell models. However, the mechanism of carvacrol-induced Ca(2+) movement and cytotoxicity is not fully understood. This study examined the effect
Samed Koc et al.
Veterinary parasitology, 193(1-3), 316-319 (2012-12-12)
The acaricidal activity of an essential oil obtained from aerial parts of Origanum bilgeri P.H. Davis (Lamiaceae), an endemic species in Turkey, and its major constituents, carvacrol was evaluated against unfed adults Rhipicephalus turanicus Pomerantzev (Acari: Ixodidae) collected from Kepez
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