- Gombapyrones, new alpha-pyrone metabolites produced by Streptomyces griseoruber Acta 3662.
Gombapyrones, new alpha-pyrone metabolites produced by Streptomyces griseoruber Acta 3662.
The Journal of antibiotics (2009-08-01)
Soleiman Helaly, Kathrin Schneider, Jonny Nachtigall, Sabaratnam Vikineswary, Geok Yuan Annie Tan, Heidi Zinecker, Johannes F Imhoff, Roderich D Süssmuth, Hans-Peter Fiedler
PMID19644516
ABSTRACT
Gombapyrones A-D, new members of the alpha-pyrone family of secondary metabolites, were produced by Streptomyces griseoruber Acta 3662, which was isolated from bamboo tree rhizosphere. The strain was characterized by its morphological and chemotaxonomical features and by 16S rDNA sequencing as S. griseobuber. The gombapyrone structures were determined by mass spectrometry and by NMR experiments, and were found to have an inhibitory activity against protein tyrosine phosphatase 1B and glycogen synthase kinase 3beta.
MATERIALS
Product Number
Brand
Product Description
Roche
Reverse Transcriptase Assay, colorimetric, suitable for enzyme immunoassay, kit of 1 (14 components), sufficient for ≤200 tests