C7786

Conalbumin from chicken egg white

BioReagent, suitable for cell culture

• Synonym(s): Ovotransferrin
• CAS Number: 1391-06-6
• EC Number: 215-727-0
• MDL number: MFCD00130856
• UNSPSC Code: 12352202
• NACRES: NA.75

Properties

• biological source: chicken egg white
• product line: BioReagent
• form: powder
• concentration: 80-100 % protein Biuret
• technique(s): cell culture | mammalian: suitable
• solubility: water: 25 mg/mL, clear to slightly hazy, pink
• cation traces: Fe: ≤0.02%
• UniProt accession no.: P02789
• shipped in: ambient
• storage temp.: −20°C
• Gene Information: chicken ... TF(396241)

Description

General description

Conalbumin, also referred to as ovotransferrin, is encoded by the avian transferrin gene in the oviduct. It is a monomeric glycoprotein consisting of 686 amino acids and is a member of transferrin family. Conalbumin is one among the abundant proteins present in the chicken egg white.

Application

Conalbumin has been used:

• as a constituent of Leibovitz 15 (L15) medium involved in preparation of primary neuronal cultures
• to study its adsorption property on a metal surface in the presence of an external electric potential
• to determine its adsorption isotherms in anion exchange chromatography by multivariate analysis

Biochem/physiol Actions

Conablumin (aka ovotransferrin) is a glycoprotein derived from egg white with a sequence similar to serum transferrin, but with a different glycosylation pattern. It is a strong iron binder with antiviral and antibacterial activities.

Conalbumin facilitates the transport of iron to the developing embryo. It exhibits anti-microbial activity thus, conalbumin is used in various applications such as infant formula ingredient, a food additive, and an antimicrobial agent for enhancing animal health. In addition, it also acts as an antifungal, antiviral, anticancer, antioxidative, antihypertensive and immunoregulatory agent.

Safety Information

• Pictograms: GHS08
• Signal Word: Danger
• Hazard Statements: H317,H334
• Precautionary Statements: P261 - P280 - P342 + P311
• Hazard Classifications: Resp. Sens. 1 - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves