Skip to Content
Merck
All Photos(1)

Documents

05-185

Sigma-Aldrich

Anti-avian Src Antibody, clone EC10

clone EC10, Upstate®, from mouse

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

EC10, monoclonal

species reactivity

avian

manufacturer/tradename

Upstate®

technique(s)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG2b

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... SRC(6714)

Specificity

specific only for avian Src; this antibody is excellent for distinguishing pp60src in cells transfected with v-src or c-src expression vectors.

Immunogen

Recombinant chicken pp60src

Application

Anti-avian Src Antibody, clone EC10 detects level of avian Src & has been published & validated for use in IP, WB & IC.

Quality

routinely evaluated in (60kDa) on a RIPA lysate of chicken embryo fibroblasts (CEF)

Target description

60 kDa

Physical form

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, with 0.05% sodium azide
Format: Purified

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Normal cells control the growth of neighboring transformed cells independent of gap junctional communication and SRC activity.
David B Alexander, Hitoshi Ichikawa, John F Bechberger, Virginijus Valiunas, Misao Ohki et al.
Cancer Research null
Transformation-specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src gene.
Reynolds, A B, et al.
Molecular and cellular biology, 9, 629-638 (1989)
Monoclonal antibodies to Rous sarcoma virus pp60src react with enzymatically active cellular pp60src of avian and mammalian origin
Parsons, S. J., et al
Journal of virology, 51, 272-282 (1984)
Wanping Xu et al.
Molecular cell, 47(3), 434-443 (2012-06-26)
Many critical protein kinases rely on the Hsp90 chaperone machinery for stability and function. After initially forming a ternary complex with kinase client and the cochaperone p50(Cdc37), Hsp90 proceeds through a cycle of conformational changes facilitated by ATP binding and
Different responses in transformation of MDCK cells in 2D and 3D culture by v-Src as revealed by microarray techniques, RT-PCR and functional assays.
Toyli, M; Rosberg-Kulha, L; Capra, J; Vuoristo, J; Eskelinen, S
Laboratory Investigation; a Journal of Technical Methods and Pathology null

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service