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671401

Sigma-Aldrich

N-Boc-N′-succinyl-4,7,10-trioxa-1,13-tridecanediamine

95% (HPLC)

Synonym(s):

17-Oxo-6,9,12-trioxa-2,16-diazaeicosanedioic acid 1-(1,1-dimethylethyl)ester

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About This Item

Empirical Formula (Hill Notation):
C19H36N2O8
CAS Number:
250612-31-8
Molecular Weight:
420.50
MDL number:
MFCD10566970
UNSPSC Code:
12352116
PubChem Substance ID:
329760420
NACRES:
NA.22

Assay

95% (HPLC)

reaction suitability

reagent type: cross-linking reagent

functional group

Fmoc
amine
carboxylic acid

storage temp.

−20°C

SMILES string

O=C(CCC(O)=O)NCCCOCCOCCOCCCNC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O

InChI

1S/C19H36N2O8/c1-19(2,3)29-18(25)21-9-5-11-27-13-15-28-14-12-26-10-4-8-20-16(22)6-7-17(23)24/h4-15H2,1-3H3,(H,20,22)(H,21,25)(H,23,24)

InChI key

RTHQDNQOODHVLK-UHFFFAOYSA-N

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Maria Davydova et al.
Journal of visualized experiments : JoVE, (145) (2019-03-26)
Maleimide-bearing bifunctional probes have been employed for decades for the site-selective modification of thiols in biomolecules, especially antibodies. Yet maleimide-based conjugates display limited stability in vivo because the succinimidyl thioether linkage can undergo a retro-Michael reaction. This, of course, can

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