568562
Poly(L-lactide-co-caprolactone-co-glycolide)
L-lactide 70 %, average Mn ~50,000 by GPC
Synonym(s):
ε-Caprolactone-glycolide-L -lactide copolymer, Poly-L -lactide-co-glycolide-co-ε-caprolactone
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About This Item
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form
solid
feed ratio
lactide:caprolactone:glycolide 70:20:10
mol wt
average Mn ~50,000 by GPC
composition
L-lactide, 70%
transition temp
Tg ~28 °C
storage temp.
2-8°C
Related Categories
Application
Poly(L-lactide-co-caprolactone-co-glycolide) (PLGA-PCL) is a biodegradable block copolymer that may be used as nanoparticle-based drug delivery systems. Electrospun nanofiber blend of PLGA-PCL, phosphorylcholine groups and an antiproliferative (rapamycin)may be used as vascular grafts and prostheses.
Features and Benefits
Biocompatible, biodegradable polymer.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Preparation of electrospun poly (L-lactide-co-caprolactone-co-glycolide)/phospholipid polymer/rapamycin blended fibers for vascular application.
Kim H I, et al.
Current Applied Physics, 9(4), e249-e251 (2009)
Novel docetaxel-loaded nanoparticles based on poly (lactide-co-caprolactone) and poly (lactide-co-glycolide-co-caprolactone) for prostate cancer treatment: formulation, characterization, and cytotoxicity studies.
Sanna V, et al.
Nanoscale Research Letters, 6(1), 260-260 (2011)
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