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Nucleic Acid Purification

The purity, quality, and quantity of your nucleic acid samples depends on reliable nucleic acid purification reagents and kits. We offer a variety of suitable kits for your nucleic acid sample needs, including gDNA, RNA, and plasmid purification, single spin purification, nucleic acid amplification, nucleic acid gel extraction, PCR clean-up, and more. Explore our comprehensive offering to maximize the reproducibility of your results and minimize the time spent on nucleic acid purification and related workflow needs.   

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RNA PurificationReaction Clean-UpgDNA PurificationPlasmid DNA Purification
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RNA Purification

RNA purification is a critical first step in many analyses due to the easy degradability of RNA. GenElute™ RNA purification kits enable purification of RNA from a variety of sources quickly and efficiently with minimal degradation, maximum purity, and high recovery and yield. GenElute™-E Single Spin RNA purification kits can be used to clean up RNA preps in a single spin for PCR and downstream applications.

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Reaction Clean-Up

Cleanup of PCR reactions, restriction digests, sequencing reactions, and agarose and polyacrylamide gel extracts is essential for removing contaminants such as salts, enzymes, unincorporated dNTPs, primers, ethidium bromide, and other impurities that can interfere with downstream analysis. A selection of products for cleaning up DNA and RNA from enzymatic reactions or pre-purified samples is available for flexibility and convenience.

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gDNA Purification
gDNA Purification

High yield, high quality DNA extraction and purification kits tailored to a variety of common and challenging sample types including cell culture, mammalian tissue, blood, viruses, bacteria, plant tissue, soil, water, urine, stool, PCR reactions, and agarose gel extractions.

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Plasmid DNA Purification
Plasmid DNA Purification

Plasmid DNA purification kits offered in miniprep, midiprep, maxiprep, and gigaprep sizes for small to large scale purification of plasmid DNA for molecular cloning, transformation, and recombinant protein expression applications.

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Related Categories
Oligos, qPCR Probes & Peptides
Choose custom products from our comprehensive portfolio of DNA and RNA oligos, qPCR probes and peptides as we offer numerous options for manufacturing platforms, purity levels, modifications to meet a variety of research applications.
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Sigma-Aldrich® Advanced Genomics provides cutting-edge gene editing and modulation technologies, including CRISPR, Cas9, and RNAi.
PCR & Amplification
PCR reagents, kits, whole genome amplification, PCR consumables, and thermocyclers for your PCR workflow needs.
Nucleic Acid Electrophoresis & Hybridization
Genomic analysis tools for DNA and RNA detection and quantitation, including nucleic acid stains, sample loading buffers, precast agarose gels, transfer membranes, as well as biotin, fluorescein, and DIG RNA and DNA labeling reagents.
Cloning & Expression
Explore our comprehensive offering of restriction enzymes, protein expression vectors, transfection reagents and protein expression technologies for your molecular cloning and protein expression workflow needs.
NGS Library Preparation
Prepare your library for next-gen sequencing. Isolate, fragment, repair, and link nucleic acids with adapters using ligation or tagmentation methods. Essential step before DNA/RNA sequencing.
Microbiome
Comprehensive Gut Microbiome Analysis: Uncover a holistic solution encompassing sample prep, sequencing, bioinformatics, and statistics. From 16S to WGS.
Roche Life Science Products
Roche Life Science Products provide dependable reagents for breakthrough research, ensuring high-quality, reproducible results.
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