All Photos(1)

Key Documents

COO/COA

View All Documentation

T5824

TAN-67 dihydrobromide

Name: TAN-67 dihydrobromide
Brand: SIGMA

≥98% (HPLC), solid

Synonym(s):

(3-Hydroxyphenyl)-1,2,3,4,4a,5,12,12aa-octahydroquinolino[2,3,3-g]isoquinoline dihydrobromide, SB-205607 dihydrobromide

Sign Into View Organizational & Contract Pricing

All Photos(1)

About This Item

Empirical Formula (Hill Notation):

C₂₃H₂₄N₂O · 2HBr

CAS Number:

148545-09-9

Molecular Weight:

506.27

MDL number:

MFCD05865267

UNSPSC Code:

12352200

description

Store tightly sealed under nitrogen

assay

≥98% (HPLC)

form

solid

color

off-white

solubility

H₂O: soluble >20 mg/mL

storage temp.

2-8°C

SMILES string

Br[H].Br[H].[H][C@@]12CN(C)CC[C@]1(Cc3nc4ccccc4cc3C2)c5cccc(O)c5

Biochem/physiol Actions

Potent, selective non-peptide δ opioid receptor agonist.

Legal Information

Sold for research purposes under agreement from GlaxoSmithKline

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Delta opioid agonists and volatile anesthetics facilitate cardioprotection via potentiation of K(ATP) channel opening.

Hemal H Patel et al.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 16(11), 1468-1470 (2002-09-03)

Opioids and volatile anesthetics produce marked cardioprotective effects against myocardial infarction via the activation of ATP-sensitive potassium (K(ATP)) channels, however, the effect of combined treatment with both drugs is unknown. We examined the hypothesis that opioids and volatile anesthetics potentiate

Dependence of delta1-opioid receptor-induced cardioprotection on a tyrosine kinase-dependent but not a Src-dependent pathway.

R M Fryer et al.

The Journal of pharmacology and experimental therapeutics, 299(2), 477-482 (2001-10-17)

We investigated the possibility that opioids activate a tyrosine kinase (TK) that mediates cardioprotection in an in vivo rat model of myocardial infarction. All animals underwent 30 min of regional ischemia and 2 h of reperfusion. Infarct size was expressed

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service