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T0283

Calcitonin rat

Name: Calcitonin rat
Brand: SIGMA

≥95% (HPLC), powder

Synonym(s):

Thyrocalcitonin

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About This Item

Empirical Formula (Hill Notation):

C₁₄₈H₂₂₈N₄₀O₄₆S₃

CAS Number:

11118-25-5

Molecular Weight:

3399.83

MDL number:

MFCD00133857

UNSPSC Code:

51111800

PubChem Substance ID:

24899879

assay

≥95% (HPLC)

form

powder

UniProt accession no.

P01257
P01256

storage temp.

−20°C

SMILES string

CCC(C)C(NC(=O)C(CO)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C1CCCN1C(=O)C(Cc2ccccc2)NC(=O)C(NC(=O)C(Cc3cnc[nH]3)NC(=O)C(Cc4ccccc4)NC(=O)C(CCCCN)NC(=O)C(CC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(CC(O)=O)NC(=O)C(CCC(N)=O)NC(=O)C(NC(=O)C(Cc5ccc(O)cc5)NC(=O)C(NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CCSC)NC(=O)C6CSSCC(N)C(=O)NCC(=O)NC(CC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(C(C)O)C(=O)N6)C(C)O)C(C)O)C(C)O)C(C)O)C(=O)NCC(=O)NC(C(C)C)C(=O)NCC(=O)NC(C)C(=O)N7CCCC7C(N)=O

Gene Information

rat ... Calca(24241)

Amino Acid Sequence

Cys-Gly-Asn-Leu-Ser-Thr-Cys-Met-Leu-Gly-Thr-Tyr-Thr-Gln-Asp-Leu-Asn-Lys-Phe-His-Thr-Phe-Pro-Gln-Thr-Ser-Ile-Gly-Val-Gly-Ala-Pro-NH₂ [Disulfide Bridge: 1-7]

Biochem/physiol Actions

Hypocalcemic hormone produced by the parafollicular C cells of the thyroid or by the ultimobranchial bodies of nonmammalian vertebrates. Decreases blood calcium and phosphate due to inhibition of resorption by osteoblasts and osteocytes.

Other Notes

32 amino acid polypeptide, 8 of which are conserved across all species.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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