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Key Documents

R7502

Sigma-Aldrich

Roridin A from Myrothecium sp.

powder, ≥98% (TLC)

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About This Item

Empirical Formula (Hill Notation):
C29H40O9
CAS Number:
Molecular Weight:
532.62
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

assay

≥98% (TLC)

form

powder

solubility

chloroform: ≥10 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

CC(O)C1OCCC(C)C(O)C(=O)OCC23CCC(C)=CC2OC4CC(OC(=O)\C=C\C=C\1)C3(C)C45CO5

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 2 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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B B Jarvis et al.
Natural toxins, 4(2), 58-71 (1996-01-01)
Samples of the toxic Brazilian plant, Baccharis coridifolia, which is responsible for numerous cases of livestock poisoning in southern Brazil and Argentina, were collected during the growing season, and the toxicities in calves of the plant materials were correlated with
G Hunder et al.
Natural toxins, 2(3), 120-123 (1994-01-01)
Lethal doses of the trichothecene mycotoxins T-2 toxin (1.5 mg/kg), diacetoxyscirpenol (DAS; 2.3 mg/kg) or roridin A (1.3 mg/kg) were intravenously administered to rats. When rats were treated with either activated charcoal (Superchar liquid, Norit A; 1 g/kg, po) or
T D Kimbrough et al.
Toxicology letters, 70(2), 165-170 (1994-02-01)
The ex vivo biophysical response of isolated rat aorta to T-2 toxin, diacetoxyscirpenol (DAS) and Roridin-A were determined. Roridin-A caused a dose-dependent relaxation of precontracted (30 mM KCl) aorta, while T-2 toxin and DAS were without effect. On the other
Zahidul Islam et al.
Toxicological sciences : an official journal of the Society of Toxicology, 98(2), 526-541 (2007-05-08)
Macrocyclic trichothecene mycotoxins produced by indoor air molds potentially contribute to symptoms associated with damp building illnesses. The purpose of this investigation was to determine (1) the kinetics of nasal inflammation and neurotoxicity after a single intranasal instillation of roridin
J A Roach et al.
Biomedical & environmental mass spectrometry, 18(1), 64-70 (1989-01-01)
A capillary supercritical fluid chromatography/mass spectrometry interface incorporating a heated frit restrictor is described. The trichothecene mycotoxins T-2 toxin, deoxynivalenol and roridin A were used to evaluate the effect of restrictor temperature and carbon dioxide mobile phase on the negative

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