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P2803

Sigma-Aldrich

N-(6-Phenylhexyl)-5-chloro-1-naphthalenesulfonamide

Synonym(s):

SC-9

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About This Item

Empirical Formula (Hill Notation):
C22H24ClNO2S
CAS Number:
102649-78-5
Molecular Weight:
401.95
MDL number:
MFCD00065544
UNSPSC Code:
12352202
PubChem Substance ID:
24898364
NACRES:
NA.77

form

solid

storage temp.

−20°C

SMILES string

Clc1cccc2c(cccc12)S(=O)(=O)NCCCCCCc3ccccc3

InChI

1S/C22H24ClNO2S/c23-21-15-8-14-20-19(21)13-9-16-22(20)27(25,26)24-17-7-2-1-4-10-18-11-5-3-6-12-18/h3,5-6,8-9,11-16,24H,1-2,4,7,10,17H2

InChI key

YUXMTDYHFPRPLG-UHFFFAOYSA-N

Biochem/physiol Actions

Activates protein kinase C in a Ca2+-dependent manner

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
108K1672
118H0452

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K Ashizawa et al.
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The signal transduction pathways involved in the regulation of the acrosome reaction and motility of fowl spermatozoa were investigated. The motility and acrosomal integrity of fowl spermatozoa in TES/NaCl buffer, with or without homogenised inner perivitelline layers (IPVL), prepared from
M Kavaliers et al.
Brain research, 554(1-2), 65-71 (1991-07-19)
There is substantial evidence that magnetic fields can reduce opiate-induced analgesia, with alterations in calcium channel function and/or calcium ion flux being implicated in the mediation of these inhibitory effects. The present experiments were designed to examine the effects of
J Bargon et al.
The Journal of biological chemistry, 267(23), 16056-16060 (1992-08-15)
Epithelial cells utilize at least two types of apical Cl- channels, the cAMP-activated cystic fibrosis transmembrane conductance regulator (CFTR) and the Ca2+/calmodulin-dependent Cl- channel. While phorbal ester (PMA) activates only CFTR-dependent Cl- secretion and the Ca2+ ionophore A23187 only the
Mohamed I Husseiny et al.
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Salmonella enterica is a versatile live carrier for the presentation of recombinant vaccine antigens. Fusion proteins of a type III secretion system effector and heterologous vaccine antigens can be translocated by live attenuated Salmonella strains and mediate protective immunity against
B Petersen et al.
Cell biology and toxicology, 10(4), 219-230 (1994-08-01)
TGF-beta 1 is known as a potent inhibitor of proliferation of rat and human hepatocytes. In this study we show that the effects of TGF-beta 1 are quite different on mouse hepatocytes. In rat and human hepatocytes, TGF-beta 1 inhibited
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