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Key Documents

O3632

Sigma-Aldrich

Osteocalcin Fragment 7-19 human

≥97% (HPLC)

Synonym(s):

Gly-Ala-Pro-Val-Pro-Tyr-Pro-Asp-Pro-Leu-Glu-Pro-Arg

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About This Item

Empirical Formula (Hill Notation):
C65H98N16O19
CAS Number:
Molecular Weight:
1407.57
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

assay

≥97% (HPLC)

UniProt accession no.

storage temp.

−20°C

SMILES string

CC(C)CC(NC(=O)C1CCCN1C(=O)C(CC(O)=O)NC(=O)C2CCCN2C(=O)C(Cc3ccc(O)cc3)NC(=O)C4CCCN4C(=O)C(NC(=O)C5CCCN5C(=O)C(C)NC(=O)CN)C(C)C)C(=O)NC(CCC(O)=O)C(=O)N6CCCC6C(=O)NC(CCCNC(N)=N)C(O)=O

InChI

1S/C65H98N16O19/c1-34(2)30-41(53(88)71-39(22-23-50(84)85)60(95)78-26-8-13-44(78)54(89)72-40(64(99)100)12-6-24-69-65(67)68)73-55(90)45-14-9-28-80(45)62(97)43(32-51(86)87)75-56(91)46-15-10-27-79(46)61(96)42(31-37-18-20-38(82)21-19-37)74-57(92)47-16-11-29-81(47)63(98)52(35(3)4)76-58(93)48-17-7-25-77(48)59(94)36(5)70-49(83)33-66/h18-21,34-36,39-48,52,82H,6-17,22-33,66H2,1-5H3,(H,70,83)(H,71,88)(H,72,89)(H,73,90)(H,74,92)(H,75,91)(H,76,93)(H,84,85)(H,86,87)(H,99,100)(H4,67,68,69)

InChI key

XEVUUFOXAJNOGZ-UHFFFAOYSA-N

Gene Information

human ... BGLAP(632)

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Other Notes

Calcium-binding protein fragment.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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H Jüppner et al.
Calcified tissue international, 39(5), 310-315 (1986-11-01)
Radioiodination of synthetic human 37-49 osteocalcin requires optimal labeling conditions in order to obtain a maximum of mono- and di-iodinated tracer with little contamination by tri- and tetra-iodinated products or "radio-damage." The antibody raised against osteocalcin(h37-49) had the highest affinity
P V Hauschka
Haemostasis, 16(3-4), 258-272 (1986-01-01)
Osteocalcin is an abundant Ca2+-binding protein indigenous to the organic matrix of bone, dentin, and possibly other mineralized tissues. This protein contains 47-50 amino acid residues (molecular weight 5,200-5,900) depending on the species. Osteocalcin is distinguished by its content of
P Pastoureau et al.
Clinical chemistry, 36(9), 1620-1624 (1990-09-01)
Most RIAs of serum bone gla-protein (BGP; also called osteocalcin) used for clinical investigation are based on bovine BGP for standard, tracer, and immunogen because of the homology between bovine and human BGP. However, ovine BGP differs from human BGP

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