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Key Documents

O1382

Sigma-Aldrich

Ochratoxin B

from Aspergillus ochraceus

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About This Item

Empirical Formula (Hill Notation):
C20H19NO6
CAS Number:
Molecular Weight:
369.37
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

biological source

Aspergillus ochraceus

storage temp.

2-8°C

SMILES string

CC1Cc2ccc(C(=O)NC(Cc3ccccc3)C(O)=O)c(O)c2C(=O)O1

pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Günter Müller et al.
Toxicology, 199(2-3), 251-259 (2004-05-19)
Modulating effects of ochratoxin A (OTA) and some of its derivatives on viability and oxidative burst activity of porcine monocytes and granulocytes have been studied. The formation of free oxygen radicals by monocytes was suppressed by OTA and ochratoxin C
S E Lee et al.
Food additives and contaminants, 24(4), 391-397 (2007-04-25)
The effects of four alkaloids on the biosynthesis of ochratoxin A (OTA), ochratoxin B (OTB) and citrinin were examined on four OTA-producing aspergilli: Aspergillus auricomus, A. sclerotiorum and two isolates of A. alliaceus. Piperine and piperlongumine, natural alkaloids of Piper
Mikiko Uchigashima et al.
Methods (San Diego, Calif.), 56(2), 180-185 (2011-09-29)
Two kinds of monoclonal antibodies (MoAbs), OCA-10A and OCA-1B, were prepared based on their specificity to ochratoxin A (OTA) and ochratoxin B (OTB) and on their tolerance to 40% methanol. In an indirect competitive enzyme-linked immunosorbent assay, the half maximal
Alexandra H Heussner et al.
Toxins, 2(6), 1582-1594 (2010-06-01)
A monoclonal antibody specific to ochratoxin B (OTB) was employed for the development of an indirect competitive OTB-ELISA. The optimized OTB-ELISA resulted in a limit of detection (LOD) for OTB of 3 µg/L (8 nM), a limit of quantification (LOQ)
Angela Mally et al.
Toxicology and applied pharmacology, 206(1), 43-53 (2005-06-21)
Ochratoxin B (OTB), a secondary metabolite of Aspergillus ochraceus, is the nonchlorinated analogue of the mycotoxin ochratoxin A (OTA), which is one of the most potent renal carcinogens in rodents. Despite the closely related structure, OTB is considered to be

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