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O1252

Sigma-Aldrich

Octopine Dehydrogenase from queen scallop

lyophilized powder, ≥5 units/mg protein

Synonym(s):

N2-(1-Carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine forming)

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About This Item

CAS Number:
Enzyme Commission number:
MDL number:
UNSPSC Code:
12352204

form

lyophilized powder

specific activity

≥5 units/mg protein

composition

Protein, ≥60% Lowry

storage temp.

2-8°C

General description

Octopine dehydrogenase (OcDH) is from the adductor muscle of a scallop and it catalyses the NADH-dependent condensation of l-arginine and pyruvate to d-octopine, NAD(+) and water during escape swimming and subsequent recovery.

Application

Octopine dehydrogenase has been used in a study to assess metabolic and physiological responses in tissues of the long-lived bivalve Arctica islandica to oxygen deficiency. It has also been used in a study to investigate biochemical responses of the marine mussel Mytilus galloprovincialis to petrochemical environmental contamination.

Biochem/physiol Actions

Octopine Dehydrogenase activity can be inhibited by treatment with the dialdehyde, o-phthalaldehyde.

Unit Definition

One unit will form 1.0 μmole of octopine from 1.0 μmole of pyruvate and 1.0 μmole of L-arginine per min. at pH 6.6 at 25 °C.

Physical form

Contains Tris buffer salts

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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B A Seibel et al.
The Biological bulletin, 198(2), 284-298 (2000-04-29)
The present study attempts to correlate the metabolism and locomotory behavior of 25 species of midwater Cephalopoda from California and Hawaii with the maximal activities of key metabolic enzymes in various locomotory muscle tissues. Citrate synthase (CS) and octopine dehydrogenase
J Jakowitsch et al.
The Plant journal : for cell and molecular biology, 17(2), 131-140 (1999-03-13)
One type of homology-dependent gene silencing in transgenic plants involves a silencing locus that is able to transcriptionally inactivate and methylate an unlinked target locus with which it shares sequence identity in promoter regions. In a manner resembling paramutation of
Rhonda C Foley et al.
FEBS letters, 563(1-3), 141-145 (2004-04-06)
TGA/OBF family members are bZIP transcription factors that bind to the octopine synthase (ocs) element, a plant promoter sequence that has been strongly linked to defence/stress responses. Intron-containing hairpin (ihp) constructs were used to generate Arabidopsis lines with reduced expression
Julia Strahl et al.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 158(4), 513-519 (2010-12-28)
In Arctica islandica, a long lifespan is associated with low metabolic activity, and with a pronounced tolerance to low environmental oxygen. In order to study metabolic and physiological responses to low oxygen conditions vs. no oxygen in mantle, gill, adductor
Rui Rosa et al.
Physiological and biochemical zoology : PBZ, 82(5), 419-429 (2009-03-07)
We examined the oxygen consumption rates and activity levels of respiratory enzymes involved in the aerobic (citrate synthase [CS]) and anaerobic (octopine dehydrogenase [ODH]) metabolism of gonatid squids (Gonatus onyx and Gonatus pyrus) as a function of body size. The

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