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M6877

Sigma-Aldrich

α-Methyl-DL-serine

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About This Item

Empirical Formula (Hill Notation):
C4H9NO3
CAS Number:
Molecular Weight:
119.12
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.26

assay

≥98% (TLC)

form

powder

color

white

SMILES string

CC(N)(CO)C(O)=O

InChI

1S/C4H9NO3/c1-4(5,2-6)3(7)8/h6H,2,5H2,1H3,(H,7,8)

InChI key

CDUUKBXTEOFITR-UHFFFAOYSA-N

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Biochem/physiol Actions

α-Methyl-DL-serine is an amino acid derivative.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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E Altmann et al.
International journal of peptide and protein research, 32(5), 344-351 (1988-11-01)
The conformational behaviour of host-guest peptides of the type Ac-Ala-Xxx-Ala-Ala-Xxx-Ala-Ala-Xxx-Ala-Ala-NH-PEGM (Xxx = alpha-aminoisobutyric acid (Aib), (S)-2-ethylalanine ((S)-Iva), (S)-2-methylserine ((S)-alpha-MeSer)) has been studied by CD spectroscopy in CF3CH2OH, CH3OH, and water and by i.r. spectroscopy in CHCl3 and in the solid
Alberto Fernández-Tejada et al.
The Journal of organic chemistry, 74(24), 9305-9313 (2009-11-21)
The synthesis and the conformational analysis in aqueous solution of a peptide and a glycopeptide containing the sequence threonine-alanine-alanine (Thr-Ala-Ala) are reported. Furthermore, the threonine residue has been replaced by the quaternary amino acid alpha-methylserine (MeSer) and their corresponding non-natural
Yong-Chul Jeong et al.
Organic & biomolecular chemistry, 9(19), 6663-6669 (2011-08-17)
An efficient strategy for the control of the chemoselectivity in Dieckmann ring closures leading to tetramic acids derived from serine and α-methyl serine is reported, and this provides pathways to diversely substituted systems from a common starting material.
An approach to enantioselective activation of N-benzoyl-alpha-methylserine with chiral N-triazinylammonium chloride.
Beata Kolesińska et al.
Acta poloniae pharmaceutica, 63(5), 426-429 (2007-03-16)
I S Mendelson
Journal of mental deficiency research, 26 (Pt 2), 107-110 (1982-06-01)
An inherited defect in the glycine cleavage enzyme results in the condition of neonatal glycine encephalopathy which has not responded to the current innovative methods of therapy. A re-examination of the enzyme structure and metabolic pathways, leads us to recommend

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