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Key Documents

M6779

Sigma-Aldrich

Small Cardioactive Peptide B

≥97% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C52H80N14O11S2
CAS Number:
Molecular Weight:
1141.41
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

assay

≥97% (HPLC)

storage temp.

−20°C

SMILES string

CSCCC(N)C(=O)NC(CC(N)=O)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(Cc2ccccc2)C(=O)N3CCCC3C(=O)NC(CCCNC(N)=N)C(=O)NC(CCSC)C(N)=O

Amino Acid Sequence

Met-Asn-Tyr-Leu-Ala-Phe-Pro-Arg-Met-NH2

Biochem/physiol Actions

Cardioactive peptide originally isolated from Aplysia.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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S L Hooper et al.
Brain research, 657(1-2), 337-341 (1994-09-19)
Application of small cardioactive peptide (SCP) or stimulation of motorneuron B15 increases the level of activated cAMP-dependent protein kinase (cAPK) in the ARC muscle. SCP application also appears to induce a translocation of cAPK between different subcellular compartments of the
S Sugita et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 17(19), 7237-7244 (1997-09-20)
The synaptic connections between the sensory neurons of Aplysia and their follower neurons have been used as a model system for examining the cellular mechanisms contributing to neuronal and synaptic plasticity. Recent studies suggest that at least two protein kinases
Stacia B Moffett et al.
Journal of insect science (Online), 5, 20-20 (2005-12-13)
In all life stages, the gut of the mosquito is innervated by a small number (typically 4) of central neurons immunoreactive to serotonin (SI). The serotonergic system appears to pass through metamorphosis largely intact, despite extensive remodeling of the gut.
M E Ferretti et al.
Neurochemistry international, 28(4), 417-424 (1996-04-01)
The effect of serotonin, FMRFamide and the small cardioactive peptide B (SCPB) on adenylate cyclase activity of the central nervous system and some peripheral organs of the freshwater snail Planorbarius corneus was investigated. The amine and the cardioactive peptide stimulated
T P Norekian et al.
The Journal of experimental zoology, 270(2), 136-147 (1994-10-01)
Effects of small cardioactive peptide B (SCPB) on cerebral neurons which underlie prey capture in the carnivorous pteropod mollusc, Clione limacina, were investigated. SCPB in concentrations of 10 microM and higher produced direct activation of cerebral ganglion neurons underlying extrusion

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