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Key Documents

L6770

Sigma-Aldrich

Lacto-N-tetraose

from human milk, ≥95% (HPAE/PAD)

Synonym(s):

β-D-Gal-(1→3)-β-D-GlcNAc-(1→3)-β-D-Gal-(1→4)-D-Glc, LNT

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About This Item

Empirical Formula (Hill Notation):
C26H45NO21
CAS Number:
Molecular Weight:
707.63
Beilstein/REAXYS Number:
4780271
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:

biological source

human milk

assay

≥95% (HPAE/PAD)

storage temp.

2-8°C

SMILES string

CC(=O)N[C@H]1[C@@H](O[C@H](CO)[C@@H](O)[C@@H]1O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)O[C@H]3[C@@H](O)[C@@H](CO)O[C@@H](O[C@H]4[C@H](O)[C@@H](O)C(O)O[C@@H]4CO)[C@@H]3O

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Florian Baumgärtner et al.
Chembiochem : a European journal of chemical biology, 15(13), 1896-1900 (2014-07-22)
Human milk oligosaccharides (HMOs) constitute the third most abundant solid component of human milk. HMOs have been demonstrated to show positive effects on the infant's well-being. Despite numerous studies, more physiological analyses of single compounds are needed to fully elucidate
Christopher E Von Seggern et al.
Journal of the American Society for Mass Spectrometry, 14(10), 1158-1165 (2003-10-08)
An investigation of sugar-sugar noncovalent complex fragmentation was conducted using a 2.94 microm Er:YAG laser for infrared (IR) atmospheric pressure matrix-assisted laser desorption/ionization (AP MALDI) on an ion trap mass spectrometer (ITMS). This approach allowed the analysis of weak noncovalent
Wengang Chai et al.
Archives of biochemistry and biophysics, 434(1), 116-127 (2005-01-05)
We have isolated and characterised two neutral oligosaccharides, one nonfucosylated and the other monofucosylated, from human milk that are based on the doubly branched lacto-N-decaose core. Their structures have been determined by a combined use of electrospray tandem mass spectrometry
G V Coppa et al.
Advances in experimental medicine and biology, 501, 307-314 (2002-01-15)
Human milk contains a large amount of oligosaccharides, which represent its third largest solute. Nevertheless, both the metabolism and the role of these substances are still largely unknown. A previous study we conducted documented that the amount of oligosaccharides excreted
E Difilippo et al.
Journal of agricultural and food chemistry, 63(19), 4805-4814 (2015-05-01)
Colostrum oligosaccharides are known to exhibit prebiotic and immunomodulatory properties. Oligosaccharide composition is species-specific, and equine colostrum has been reported to contain unique oligosaccharides. Therefore, equine oligosaccharides (EMOS) from colostrum from different horse breeds were analyzed by CE-LIF, CE-MS(n), HILIC-MS(n)

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