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I9281

Sigma-Aldrich

5′-Iodoresiniferatoxin

solid

Synonym(s):

6,7-Deepoxy-6,7-didehydro-5-deoxy-21-dephenyl-21-(phenylmethyl)-daphnetoxin,20-(4-hydroxy-5-iodo-3-methoxybenzeneacetate), I-RTX

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About This Item

Empirical Formula (Hill Notation):
C37H39IO9
Molecular Weight:
754.60
MDL number:
MFCD09971003
UNSPSC Code:
12352200
PubChem Substance ID:
24896153

form

solid

color

white

solubility

DMSO: soluble 10 mg/mL

storage temp.

−20°C

SMILES string

COc1cc(CC(=O)OCC2=CC3C4OC6(Cc5ccccc5)O[C@]4(C[C@@H](C)[C@]3(O6)C7C=C(C)C(=O)[C@@]7(O)C2)C(C)=C)cc(I)c1O

InChI

1S/C37H39IO9/c1-20(2)35-16-22(4)37-26(33(35)45-36(46-35,47-37)18-23-9-7-6-8-10-23)12-25(17-34(42)29(37)11-21(3)32(34)41)19-44-30(39)15-24-13-27(38)31(40)28(14-24)43-5/h6-14,22,26,29,33,40,42H,1,15-19H2,2-5H3/t22-,26+,29-,33-,34-,35-,36?,37-/m1/s1

InChI key

TZUJORCXGLGWDV-RYACRXIZSA-N

Biochem/physiol Actions

Vanilloid receptor antagonist.

Legal Information

Sold in France, Germany, Great Britain and Switzerland under a patent license, restricted to research use only, from Procyon Pharmaceuticals, Inc.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Nirlipta Swain et al.
Frontiers in cell and developmental biology, 10, 867057-867057 (2022-10-11)
Bi-directional crosstalk between Ca2+ signaling and ROS modulates physiological processes as a part of a regulatory circuit including sperm function. The role of transient receptor potential vanilloid 1 (TRPV1) in this regard cannot be undermined. This is the first report

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