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Key Documents

I3271

Sigma-Aldrich

Interleukin-6 Fragment 88-121 human

≥80% (HPLC)

Synonym(s):

IL-6 (88-121)

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
51111800

biological source

human

assay

≥80% (HPLC)

form

solid

composition

Peptide content, ~70%

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... IL6(3569)

Biochem/physiol Actions

Competitively inhibits binding of IL-6 to its receptor.

Quality

Up to 20% of the methionine residue may be present as the sulfoxide.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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T Ekida et al.
Biochemical and biophysical research communications, 189(1), 211-220 (1992-11-30)
In order to locate the receptor-binding region of human interleukin-6 (IL-6), twelve peptide fragments were prepared by digestion of IL-6 with lysylendopeptidase. A significant activity of the receptor-binding was observed only for a peptide Ile88-Lys121, although the activity was estimated

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