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About This Item
Empirical Formula (Hill Notation):
C4H9NO4S
CAS Number:
Molecular Weight:
167.18
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
Recommended Products
assay
≥98% (TLC)
storage temp.
−20°C
SMILES string
NC(CCS(O)=O)C(O)=O
InChI
1S/C4H9NO4S/c5-3(4(6)7)1-2-10(8)9/h3H,1-2,5H2,(H,6,7)(H,8,9)
InChI key
PDNJLMZEGXHSCU-UHFFFAOYSA-N
Biochem/physiol Actions
Neurotransmitter candidate
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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E R Whittemore et al.
European journal of pharmacology, 192(3), 435-438 (1991-01-17)
Quisqualic acid sensitizes hippocampal CA1 neurons to depolarization by L-2-amino-4-phosphonobutanoic acid (L-AP4). This sensitization to L-AP4 is known to be blocked by simultaneous exposure to L-homocysteinesulfinic acid, L-alpha-aminoadipic acid and L-serine-O-sulfate during exposure to quisqualate. We report here that these
G A Thompson et al.
Neuropharmacology, 34(8), 857-863 (1995-08-01)
Depolarizations induced by a range of amino acids including some sulphur-containing excitatory transmitter candidates were evoked from motoneurones in the neonatal rat spinal cord under conditions that precluded activation of known ionotropic glutamate receptors. The responses could be partially and
Philipp Görtz et al.
Journal of the neurological sciences, 218(1-2), 109-114 (2004-02-05)
Severe hyperhomocysteinemia (50-200 microM) often presents itself with acute neuronal dysfunction including seizures and psychosis. Its moderate form (15-50 microM) is associated with cognitive impairment and dementia. We investigated the neuropharmacological effects of homocysteine and its oxidized forms, homocysteinesulfinic acid
A Becker et al.
International journal of clinical pharmacology and therapeutics, 45(9), 504-515 (2007-10-03)
Interference of methotrexate (MTX) with the metabolism of homocysteine may contribute to MTX neurotoxicity. In this pilot study we measured the concentration of homocysteine and related metabolites in the cerebrospinal fluid (CSF) of patients with primary central nervous system lymphoma
M J Neal et al.
British journal of pharmacology, 105(3), 563-568 (1992-03-01)
1. The effects of the sulphur containing amino acids, homocysteic acid, homocysteine sulphinic acid, cysteic acid and cysteine sulphinic acid on the release of [3H]-acetylcholine ([3H]-ACh) from the cholinergic amacrine cells of the rabbit retina were examined. 2. All the
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