All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C15H15NO7
CAS Number:
Molecular Weight:
321.28
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
assay
≥95%
form
powder
color
light green
SMILES string
O[C@@H]1[C@H](O[C@H]([C@H](O)[C@H]1O)C(O)=O)Oc2cccc3cccnc23
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Substrates
Substrate for the histochemical demonstration of β-glucuronidase and for quantitative assay systems.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Direct radioiodination of metabolic 8-hydroxy-quinolyl-glucuronide, as a potential anti-cancer drug.
T Unak et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 47(7), 645-647 (1996-07-01)
8-Hydroxy-quinolyl-glucuronide (8-HOQ-Glu) can be deglucuronidated by the beta-glucoronidase enzyme, which has an activity that is considerably high in certain kinds of cancer cell. Owing to this enzyme activity, 8-HOQ-Glu can be considered as a potential anti-cancer drug. The combination of
Andrew D Pris et al.
Analytical chemistry, 81(24), 9948-9954 (2009-11-18)
Enabling trace chemical detection equipment utilized in the field to transduce a biodetection assay would be advantageous from a logistics, training, and maintenance standpoint. Described herein is an assay design that uses an unmodified, commercial off-the-shelf (COTS) ion trap mobility
Peter Tobin et al.
British journal of clinical pharmacology, 62(1), 122-129 (2006-07-18)
Irinotecan (CPT-11) is a prodrug that is used to treat metastatic colorectal cancer. It is activated to the topoisomerase poison SN-38 by carboxylesterases. SN-38 is metabolized to its inactive glucuronide, SN-38 glucuronide. The aim of this study was to determine
T P Monson et al.
International journal of radiation oncology, biology, physics, 20(6), 1263-1271 (1991-06-01)
RIF-1 mouse tumors express high levels of beta-glucuronidase activity relative to most normal tissues. The high activity can be exploited for targeting specific drugs preferentially to tumor tissues. In this study we examined the kinetics of 8-hydroxyquinoline (8-OHQ) accumulation in
A L James et al.
Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology, 267(3), 316-321 (1988-01-01)
The use of 8-hydroxyquinoline-beta-D-glucuronide for the demonstration of beta-glucuronidase activity within the family Enterobacteriaceae has been investigated. The compound has been shown to be an effective substrate for the bacterial enzyme and the Michaelis constant for the association has been
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