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Key Documents

G7522

Sigma-Aldrich

3-α-Galactobiose

synthetic, ≥90%

Synonym(s):

α-D-Gal-(1→3)-D-Gal, 3-O-α-D-Galactopyranosyl-D-galactose

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About This Item

Empirical Formula (Hill Notation):
C12H22O11
CAS Number:
Molecular Weight:
342.30
Beilstein/REAXYS Number:
83008
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:

biological source

synthetic

assay

≥90%

storage temp.

2-8°C

SMILES string

OC[C@H]1O[C@H](O[C@@H]2[C@@H](O)C(O)O[C@H](CO)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1O

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Haiying Chi et al.
Animal science journal = Nihon chikusan Gakkaiho, 83(1), 88-93 (2012-01-19)
α-1,3-Galactosyltransferase (α-GalT), an enzyme creating Galα1-3Gal (α-Gal) epitope on the cell surface in some mammalian species such as pigs, is known to be a key factor that causes hyperacute rejection upon transplantation from pigs to humans. To establish the RNA
Scott P Commins et al.
American journal of respiratory and critical care medicine, 185(7), 723-730 (2012-01-28)
IgE antibodies to the mammalian oligosaccharide galactose-α-1,3-galactose (α-gal) are common in the southeastern United States. These antibodies, which are induced by ectoparasitic ticks, can give rise to positive skin tests or serum assays with cat extract. To evaluate the relationship
Joshua L Kennedy et al.
Pediatrics, 131(5), e1545-e1552 (2013-04-10)
Despite a thorough history and comprehensive testing, many children who present with recurrent symptoms consistent with allergic reactions elude diagnosis. Recent research has identified a novel cause for "idiopathic" allergic reactions; immunoglobulin E (IgE) antibody specific for the carbohydrate galactose-α-1,3-galactose
Delayed urticaria to beef ingestion.
Henry Benjamin Coker et al.
Journal of the American Academy of Dermatology, 68(3), e101-e101 (2013-02-12)
T Biedermann et al.
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 63 Suppl 1, 76-79 (2012-05-11)
Delayed immediate-type allergy to innards and red meat can be mediated by IgE antibodies to galactose-α-1, 3-galactose (α-Gal). Apart from humans and Old World apes, α-Gal is ubiquitously expressed in glycoproteins and glycolipids. Thus, as α-Gal is immunogenic for humans

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