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Key Documents

G6132

Sigma-Aldrich

Glycodeoxycholic acid monohydrate

≥97% (TLC)

Synonym(s):

3α,12α-Dihydroxy-5β-cholanoic acid N-(carboxymethyl)amide, Glycodesoxycholic acid, N-(3α,12α-Dihydroxy-24-oxocholan-24-yl)glycine

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About This Item

Linear Formula:
C26H43NO5
CAS Number:
Molecular Weight:
467.64
Beilstein/REAXYS Number:
2954947
MDL number:
UNSPSC Code:
12161900
PubChem Substance ID:

description

anionic

assay

≥97% (TLC)

SMILES string

[H]O[H].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC(=O)NCC(O)=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2

InChI

1S/C26H43NO5.H2O/c1-15(4-9-23(30)27-14-24(31)32)19-7-8-20-18-6-5-16-12-17(28)10-11-25(16,2)21(18)13-22(29)26(19,20)3;/h15-22,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32);1H2/t15-,16-,17-,18+,19-,20+,21+,22+,25+,26-;/m1./s1

InChI key

DLOTUJUSJVIXDW-YEUHZSMFSA-N

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Biochem/physiol Actions

Induces apoptosis in hepatocytes; may induce DNA cleavage.

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Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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In acute pancreatitis, local as well as systemic organ complications are mediated by the activation of various inflammatory cascades. The role of complement in this setting is unclear. The aim of the present study was to determine the level of
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Journal of gastroenterology and hepatology, 22(11), 1872-1876 (2007-10-05)
Octreotide is considered to reduce exocrine pancreatic secretion in acute hemorrhagic necrotizing pancreatitis decreasing pancreatic autodigestion. The aim of this study was to determine whether octreotide also has antioxidative effects in acute pancreatitis. Additionally time and dose of application were
Giulia de Petris et al.
The journal of physical chemistry. B, 113(20), 7162-7169 (2009-05-01)
This paper deals with electrospray ionization mass spectrometry (ESIMS), small-angle X-ray scattering (SAXS), and dynamic light scattering (DLS) measurements in order to provide information on the existence, aggregation, composition, and structure of the two-component aggregates of sodium glycocholate (NaGC) and
Yanfeng Wang et al.
International journal of pharmaceutics, 370(1-2), 68-74 (2008-12-17)
HO-1-u-1 (Ueda-1) is a human tumor cell line established from human sublingual squamous cell carcinoma. In previous study, HO-1-u-1 cell line was grown on cell culture inserts and utilized as in vitro model for screening sublingual drug delivery. The aim
Dockyu Kim et al.
Journal of microbiology and biotechnology, 17(3), 403-407 (2007-12-07)
Several marine bacterial strains, which were isolated from seawater off the island Dokdo, Korea, were screened to find new bioactive compounds such as antibiotics. Among them, Donghaeana dokdonensis strain DSW-6 was found to produce antibacterial agents, and the agents were

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