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G1876

Sigma-Aldrich

L-Glutamic acid γ-ethyl ester

Synonym(s):

L-Glutamic acid 5-ethyl ester

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About This Item

Linear Formula:
C2H5OCOCH2CH2CH(NH2)COOH
CAS Number:
1119-33-1
Molecular Weight:
175.18
Beilstein/REAXYS Number:
1725589
EC Number:
214-274-6
MDL number:
MFCD00037217
UNSPSC Code:
12352200
PubChem Substance ID:
24895078

application(s)

peptide synthesis

storage temp.

−20°C

SMILES string

CCOC(=O)CC[C@H](N)C(O)=O

InChI

1S/C7H13NO4/c1-2-12-6(9)4-3-5(8)7(10)11/h5H,2-4,8H2,1H3,(H,10,11)/t5-/m0/s1

InChI key

XMQUEQJCYRFIQS-YFKPBYRVSA-N

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

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V M Kozhanov et al.
Tsitologiia, 46(4), 326-336 (2004-09-07)
The role of group II metabotropic glutamate receptors (mGluRs) in modulation of inhibitory synaptic activity was studied by intracellular recording of motoneuron miniature inhibitory spontaneous postsynaptic potentials (mIPSPs) in isolated lumbar segments of the turtle spinal cord in the medium
Jingyi Ma et al.
Behavioural brain research, 133(1), 45-56 (2002-06-06)
The involvement of metabotropic glutamate receptor (mGluR) subtypes in the generation of hippocampal EEG (30-100 Hz) and behaviors induced by a hippocampal afterdischarge (AD) was examined in freely behaving rats. A hippocampal AD induced an increase in gamma waves (30-100
Kirsteen N Browning et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 27(34), 8979-8988 (2007-08-24)
We demonstrated previously that, by suppressing cAMP levels, metabotropic glutamate receptors (mGluRs) play a crucial role in opioid receptor trafficking on GABAergic nerve terminals within gastric brainstem vagal circuits. Using whole-cell patch-clamp recordings, we aimed to correlate the influence of
Kirsteen N Browning et al.
The Journal of physiology, 575(Pt 3), 761-776 (2006-07-11)
We demonstrated recently that increasing the levels of cAMP allows opioids to modulate GABAergic synaptic transmission between the nucleus of the tractus solitarius (NTS) and dorsal motor nucleus of the vagus (DMV). Using a combination of electrophysiological, immunohistochemical and biochemical
D Manahan-Vaughan
Neuropharmacology, 37(12), 1459-1464 (1999-01-14)
Activation of group 1 metabotropic glutamate receptors (mGluRs) has been shown to facilitate the induction of tetanically evoked long-term potentiation in vivo, whereas group 2 mGluR antagonists inhibit long-term depression (LTD) in the CA1 region. LTD has not been successfully
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