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E6500

Sigma-Aldrich

Ergonovine maleate salt

Synonym(s):

Ergometrine maleate salt

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About This Item

Empirical Formula (Hill Notation):
C19H23N3O2 · C4H4O4
CAS Number:
129-51-1
Molecular Weight:
441.48
EC Number:
204-953-5
MDL number:
MFCD00672896
UNSPSC Code:
12352200
NACRES:
NA.77

storage temp.

−20°C

SMILES string

OC(=O)\C=C/C(O)=O.C[C@@H](CO)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34

InChI

1S/C19H23N3O2.C4H4O4/c1-11(10-23)21-19(24)13-6-15-14-4-3-5-16-18(14)12(8-20-16)7-17(15)22(2)9-13;5-3(6)1-2-4(7)8/h3-6,8,11,13,17,20,23H,7,9-10H2,1-2H3,(H,21,24);1-2H,(H,5,6)(H,7,8)/b;2-1-/t11-,13+,17+;/m0./s1

InChI key

YREISLCRUMOYAY-IIPCNOPRSA-N

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Biochem/physiol Actions

Oxytocic, stimulates contraction of uterine muscle; partial agonist at serotonergic and dopaminergic receptors in CNS; selective, potent antagonist at smooth muscle serotonergic receptors.

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Tsuyoshi Ito et al.
Circulation. Cardiovascular imaging, 5(2), 226-232 (2012-02-22)
The potential of multislice CT (MSCT) to predict coronary spasm has not been elucidated. The aim of this study was to investigate whether the morphological features observed on MSCT at the site of ergonovine-induced epicardial spasm could be used as
Rany Harara et al.
The journal of obstetrics and gynaecology research, 37(9), 1203-1207 (2011-04-27)
The aim of this work was to compare the effect of intraumbilical injection of three different uterotonic solutions in the management of retained placenta. This study was conducted in Ain-Shams University Maternity Hospital, Cairo, Egypt. A total of 78 women
Wayne Siegel
The American journal of cardiology, 105(8), 1198-1199 (2010-04-15)
This article provides narration of the events during the development of ergonovine maleate infusions for detecting coronary artery spasm at the Cleveland Clinic in 1973. This was the first safe, reproduceable and reliable test for angiographic visualization of the pathophysiology
Active management of the third stage of labour.
Nasreen Aflaifel et al.
BMJ (Clinical research ed.), 345, e4546-e4546 (2012-07-10)
Hosam E Matar et al.
BMC pregnancy and childbirth, 10, 32-32 (2010-06-24)
Care for women during the third stage aims to reduce the risk of major haemorrhage, but is very variable. The current World Health Organisation (WHO) recommendation is that care should include administration of a uterotonic (oxytocin, if it is available)
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