D5814
Dihydrexidine hydrochloride
solid
Synonym(s):
(±)-trans-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine hydrochloride
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C17H16NO2 · HCl
CAS Number:
Molecular Weight:
302.78
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
form
solid
Storage temp.
2-8°C
SMILES string
Cl.Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O
Gene Information
human ... DRD1(1812)
Biochem/physiol Actions
D1 dopamine receptor agonist
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
Don't see the Right Version?
If you require a particular version, you can look up a specific certificate by the Lot or Batch number.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
M Goulet et al.
The Journal of pharmacology and experimental therapeutics, 292(2), 714-724 (2000-01-20)
Selective D(1) dopamine receptor agonists exert antiparkinsonian effects in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) monkey model of Parkinson's disease and in human Parkinson's disease. Motor impairment in idiopathic Parkinson's disease progresses from mild to severe, but the therapeutic potential of D(1) dopamine
W K Brewster et al.
Journal of medicinal chemistry, 33(6), 1756-1764 (1990-06-01)
trans-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenan thridine (4a, dihydrexidine) has been found to be a highly potent and selective agonist of the dopamine D1 receptor in rat brain. Dihydrexidine had an EC50 of approximately 70 nM in activating dopamine-sensitive rat striatal adenylate cyclase and a
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service