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D0380

Sigma-Aldrich

Nε-DNP-L-lysine hydrochloride

Synonym(s):

Nε-(2,4-Dinitrophenyl)-L-lysine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C12H16N4O6 · HCl
CAS Number:
14401-10-6
Molecular Weight:
348.74
EC Number:
238-366-0
MDL number:
MFCD00036383
UNSPSC Code:
12352200
PubChem Substance ID:
24893228

form

powder

storage temp.

−20°C

SMILES string

OC([C@@H](N)CCCCNC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1)=O.[H]Cl

InChI

1S/C12H16N4O6.ClH/c13-9(12(17)18)3-1-2-6-14-10-5-4-8(15(19)20)7-11(10)16(21)22;/h4-5,7,9,14H,1-3,6,13H2,(H,17,18);1H

InChI key

VDVXDUOPLKVMMM-UHFFFAOYSA-N

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

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K Maeyama et al.
Analytical biochemistry, 194(2), 316-325 (1991-05-01)
In rat basophilic leukemia cells (RBL-2H3), a tumor analogue of mast cells, the aggregation of IgE receptors initiates increase in the intracellular concentration of calcium ([Ca2+]i), monitored with the fluorescent Ca probe fura-2, and finally results in histamine secretion. In
R Bredehorst et al.
Analytical biochemistry, 193(2), 272-279 (1991-03-02)
We developed a novel trifunctional carrier molecule for the synthesis of hapten-fluorophore conjugates as reporter molecules in immunoassays. This carrier eliminates some of the disadvantages associated with currently used fluorophore-labeling procedures including high nonspecific binding. The backbone of the carrier
G P Holland et al.
Journal of immunological methods, 138(2), 245-255 (1991-04-25)
The influence of the epitope density of the antigen on antibody affinity values determined by fluid- and solid-phase immunoassays was assessed. The affinity of the interaction of a panel of monoclonal anti-DNP antibodies of different affinities (as determined by equilibrium
R A Hatz et al.
Gastroenterology, 98(4), 894-900 (1990-04-01)
The capacity of the stomach to participate in anaphylaxis induced by the hapten N,N'-di-2,4,dinitrophenyllysine (di-DNP-lysine) was examined in BDF1 female mice immunized with dinitrophenylated Ascaris suum extract. Immunized animals underwent laparotomy and nontraumatic pyloric occlusion using a microvascular clamp. Following
P L Amlot et al.
Clinical and experimental immunology, 64(1), 125-135 (1986-04-01)
Thymus-independent (TI) and thymus-dependent (TD) primary immune responses were measured in 67 controls and 13 bone marrow transplant (BMT) recipients treated with cyclosporine (CSP) by immunizing with a synthetic antigen (DNP-Ficoll) and keyhole limpet haemocyanin (KLH). DNP-Ficoll induced similar TI
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