Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

C7339

Sigma-Aldrich

Monoclonal Anti-Cyclin D2 antibody produced in mouse

clone DCS-3, ascites fluid

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

MDL number:
MFCD00239665
UNSPSC Code:
12352203

biological source

mouse

conjugate

unconjugated

antibody form

ascites fluid

clone

DCS-3, monoclonal

mol wt

antigen 33-35 kDa (and several lower and higher MW proteins)

contains

15 mM sodium azide

species reactivity

mouse, human

technique(s)

flow cytometry: suitable
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
indirect ELISA: suitable
microarray: suitable
western blot: 1:400 using a cultured human tumor cell line extract

isotype

IgG2a

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... CCND2(894)
mouse ... Ccnd2(12444)

Specificity

The antibody is useful in antibody-mediated knock-out experiments. The product does not cross-react with other D-type cyclins.

Immunogen

recombinant human cyclin D2 protein.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

J Lukas et al.
Oncogene, 10(11), 2125-2134 (1995-06-01)
To explore regulation and function of cyclin D2, a candidate cell cycle-regulatory proto-oncogene, we examined subcellular localisation, cell type- and cell cycle-dependent expression, and requirement of cyclin D2 protein for G1 progression, in a panel of 40 human normal and
Nathalie M Fiaschi-Taesch et al.
Diabetes, 59(8), 1926-1936 (2010-07-30)
Most knowledge on human beta-cell cycle control derives from immunoblots of whole human islets, mixtures of beta-cells and non-beta-cells. We explored the presence, subcellular localization, and function of five early G1/S phase molecules-cyclins D1-3 and cdk 4 and 6-in the
Kikumi Hata et al.
Journal of immunology (Baltimore, Md. : 1950), 173(4), 2453-2461 (2004-08-06)
The engagement of membrane-bound Igs (mIgs) results in growth arrest, accompanied by apoptosis, in the WEHI-231 murine B lymphoma cells, a cell line model representative of primary immature B cells. Inhibitor of differentiation (Id) proteins, members of the helix-loop-helix protein
Ningli Cheng et al.
PloS one, 3(4), e1911-e1911 (2008-04-03)
The effect of Bcl-2 on oncogenesis is complex and expression may either delay or accelerate oncogenesis. The pro-oncogenic activity is attributed to its well characterized anti-apoptotic function while the anti-oncogenic function has been attributed to its inhibition of cellular proliferation.
Federico Tagliati et al.
Endocrinology, 147(7), 3530-3538 (2006-04-08)
Somatostatin (SRIH) inhibits cell proliferation by interacting with five distinct SRIH receptor subtypes (SSTRs) activating several pathways in many tissues. We previously demonstrated that SRIH, by activating Src homology-2-containing protein, inhibits cell proliferation of the human medullary thyroid carcinoma cell
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service