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C3255

Sigma-Aldrich

Corynanthine

Synonym(s):

17α-Hydroxyyohimban-16β-carboxylic acid methyl ester

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About This Item

Empirical Formula (Hill Notation):
C21H26N2O3
CAS Number:
483-10-3
Molecular Weight:
354.44
EC Number:
207-590-0
MDL number:
MFCD00069659
UNSPSC Code:
12352200
PubChem Substance ID:
24892596

storage temp.

2-8°C

SMILES string

[H][C@@]12CC[C@H](O)[C@@H](C(=O)OC)[C@@]1([H])C[C@]3([H])N(CCc4c3[nH]c5ccccc45)C2

InChI

1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19-/m0/s1

InChI key

BLGXFZZNTVWLAY-DKJBZYCGSA-N

Gene Information

human ... CYP2D6(1565)

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

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Pei Chen et al.
Journal of AOAC International, 98(4), 896-901 (2015-08-14)
A single-laboratory validation was performed on a practical ultra-HPLC (UHPLC)-diode array detector (DAD)/tandem MS method for determination of yohimbine in yohimbe barks and related dietary supplements. Good separation was achieved using a Waters Acquity ethylene bridged hybrid C18 column with
Fernando Huete-Toral et al.
The Journal of pharmacology and experimental therapeutics, 352(1), 119-128 (2014-10-26)
Melatonin and its analog 5-MCA-NAT (5-methylcarboxyamino-N-acetyl tryptamine) are active compounds reducing intraocular pressure (IOP). This action is mediated through MT2 and the putative MT3 melatonin receptor, producing a transient reduction of IOP that lasts for a few hours and has

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