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Key Documents

B5277

Sigma-Aldrich

Boc-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Arg-Leu-Arg-Gly 5-aminopentylamide

≥97% (HPLC)

Synonym(s):

Boc-DAKLI

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About This Item

Empirical Formula (Hill Notation):
C87H149N31O17
CAS Number:
Molecular Weight:
1901.31
MDL number:
UNSPSC Code:
12352200

assay

≥97% (HPLC)

composition

Peptide content, ~70%

storage temp.

−20°C

Application

Used to label κ opioid receptors; precursor for the production of labeled DAKLI; can be coupled to 125I-Bolton-Hunter reagent, FITC, biotin, etc.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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A Goldstein et al.
Proceedings of the National Academy of Sciences of the United States of America, 85(19), 7375-7379 (1988-10-01)
We describe a synthetic ligand, "DAKLI" (Dynorphin A-analogue Kappa LIgand), related to the opioid peptide dynorphin A. A single reactive amino group at the extended carboxyl terminus permits various reporter groups to be attached, such as 125I-labeled Bolton-Hunter reagent, fluorescein

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