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A6882

Sigma-Aldrich

Atractyloside potassium salt

≥98% (TLC)

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About This Item

Empirical Formula (Hill Notation):
C30H44K2O16S2
CAS Number:
102130-43-8
Molecular Weight:
802.99
MDL number:
MFCD00078810
UNSPSC Code:
12352200
PubChem Substance ID:
24891150

assay

≥98% (TLC)

solubility

H2O: 20 mg/mL

SMILES string

[K+].[K+].[H][C@@]12CC[C@@]3([H])[C@]4(C)C[C@@H](C[C@@H](C(O)=O)[C@@]4([H])CC[C@]3(C1)[C@@H](O)C2=C)O[C@@H]5O[C@H](CO)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]5OC(=O)CC(C)C

Biochem/physiol Actions

An extremely toxic glycoside isolated from thistles. Inhibits oxidative phosphorylation by blocking the transfer of adenosine nucleotides through the mitochondrial membrane.

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificates of Analysis (COA)

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Sebastian A Barrientos et al.
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Biochimica et biophysica acta, 1840(12), 3404-3412 (2014-09-16)
Mitochondria are the major source of ATP to power sperm motility. Phosphorylation of mitochondrial proteins has been proposed as a major regulatory mechanism for mitochondrial bioenergetics. Sperm motility was measured by a computer-assisted analyzer, protein detection by western blotting, membrane

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