A2379
Methyl-DL-α-aminobutyrate hydrochloride
Synonym(s):
DL-α-Amino-n-butyric acid methyl ester hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C5H11NO2 · HCl
CAS Number:
Molecular Weight:
153.61
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
assay
≥98% (TLC)
form
powder
color
white
application(s)
cell analysis
storage temp.
−20°C
SMILES string
Cl.Cl.CCC(N)C(=O)OC
InChI
1S/C5H11NO2.2ClH/c1-3-4(6)5(7)8-2;;/h4H,3,6H2,1-2H3;2*1H
InChI key
DJFXABZGZUTACI-UHFFFAOYSA-N
Biochem/physiol Actions
Methyl-DL-α-aminobutyrate may be used to study the induction mechanism of concentrative uptake of L-dopa by Langerhan′s cells.
Storage Class
13 - Non Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Certificates of Analysis (COA)
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Niels Bendsöe
Upsala journal of medical sciences, 108(3), 161-192 (2004-03-06)
Various aspects concerning the L-dopa uptake mechanism into human epidermal Langerhans cells (LC) and the energy metabolism of epidermis have been examined. The study is based on the discovery of a new amino acid transport system in human epidermal LC.
Bengt Falck et al.
Experimental dermatology, 12(5), 602-609 (2004-01-07)
We have characterized a stereospecific transport mechanism for L-dopa into human epidermal Langerhans cells (LCs). It is different from any other amino acid transport system. It is highly concentrative, largely pH-independent, and independent of exogenous Na+, glucose and oxygen, and
B Falck et al.
Acta dermato-venereologica, 73(3), 197-199 (1993-06-01)
We recently reported the existence of two kinds of human epidermal Langerhans' cells (LC), one which can take up and accumulate L-dopa and one which cannot. The dopa(+) LC take up L-dopa by carrier-mediated exchange diffusion, that is, the influx
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