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Key Documents

A1477

Sigma-Aldrich

Angiostatin K1-3 human

≥90% (SDS-PAGE), recombinant, expressed in Pichia pastoris (without N-linked glycosylation)

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About This Item

MDL number:
UNSPSC Code:
12352200

recombinant

expressed in Pichia pastoris (without N-linked glycosylation)

assay

≥90% (SDS-PAGE)

form

liquid

impurities

endotoxin, tested

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... PLG(5340)

Biochem/physiol Actions

A proteolytic fragment of plasminogen containing the first three kringle structures. A specific inhibitor of endothelial cell growth and angiogenesis. More active relative to kringles 1-4. Studies with recombinant angiostatin show that the tumor inhibitory activity resides in a fragment of K1-3.

Physical form

Supplied in 0.15 M sodium chloride.

Legal Information

U.S. Patent Nos. 6,024,688; 5,861,372. Sold under license from CMCC.

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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