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Key Documents

C15605

Sigma-Aldrich

4,4′-Dithiodibutyric acid

95%

Synonym(s):

3-Carboxypropyl disulfide, Di(4-carboxybutyl) disulfide

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About This Item

Linear Formula:
[-S(CH2)3CO2H]2
CAS Number:
Molecular Weight:
238.32
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

95%

form

solid

mp

108-110 °C (lit.)

SMILES string

OC(=O)CCCSSCCCC(O)=O

InChI

1S/C8H14O4S2/c9-7(10)3-1-5-13-14-6-2-4-8(11)12/h1-6H2,(H,9,10)(H,11,12)

InChI key

YYSCJLLOWOUSHH-UHFFFAOYSA-N

General description

4,4′-Dithiodibutyric acid is an organic sulfur compound, primarily used as a cross-linking agent in the synthesis of polymers and materials.

Application

4,4′-Dithiodibutyric acid can be used as:
  • A precursor to produce novel polythioester (PTE).
  • A reactant in the production of chemically crosslinked epoxidized natural rubber.
  • An alternative monolayer for protein chips.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Genome and proteome analysis of Rhodococcus erythropolis MI2: Elucidation of the 4, 4-dithiodibutyric acid catabolism
Khairy, et al.
PLoS ONE, 11, e0167539-e0167539 (2016)
Development and characterization of 4, 4?-dithiodibutyric acid as a monolayer for protein chip
Jang, et al.
Sensors and Materials, 18, 367-380 (2006)
Biodegradation of the organic disulfide 4, 4?-dithiodibutyric acid by Rhodococcus spp
Khairy, et al.
Applied and Environmental Microbiology, 81, 8294-8306 (2015)
A Silvestri et al.
Nanoscale, 9(38), 14730-14739 (2017-09-28)
In the biomedical applications of nanoparticles (NPs), the proper choice of surface chemistry is a crucial aspect in their design. The nature of the coating can heavily impact the interaction of NPs with biomolecules, affect the state of aggregation, and

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